Normally, no. However, the IRA used loads of RPG-7s back in the day, and someone – probably RIRA – popped an RPG-22 at MI6 HQ in 2000. The most likely police reaction to the use of such a weapon on a non-political target will be "political infighting/score-settling between diehard Irish republicans," not "Russian mobsters battling MI5."
Re: miscalcualtion